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C: Ignite about 200 mg: the residue effervesces with acids, and meets the requirements of the tests for Sodiumpentobarbital will decrease the level or effect of cobimetinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Avoid coadministration. Strong or moderate CYP3A inducers may decrease cobimetinib systemic exposure b